The effect on systolic hypertension after repair of coarctation of the aorta in adults

Abstract

Background: The purpose of this retrospective study is to determine the effect of repair on systolic hypertension and the results of repair of aortaic coarctation in adults. Methods: Eight adults patients underwent aortaic coarctation surgical repair between March 1990 and October 2007. Mean age of the patients 28.5±8.59 years (range,18 to 41 years). There were 6 men and 2 women patients. Mean systolic blood pressure was 160.63±12.37 mmHg (range, 145 to 180 mmHg ). All patients were receiving two or three antihypertensive drugs preoperatively. Mean peak systolic gradient across the coarctation was 62.5±11.65 mmHg (range, 40 to 80 mmHg). Surgical treatment were performed with bypass graft between proximal and distal descendan aorta in four patients, bypass graft from the left subclavian artery to the descending aorta in three patients, patch aortaoplasty in one patient. In none of the patients there was hospital mortality or late morbidity and mortality. Results: Mean follow-up was 8.06±4.95 years (range, 1 to 17 years). There were no deaths. At the last follow-up, only two patient was normotensive without receiving any hypertensive medication. The other 6 patients were normotensive with one antihypertensive drug. Recoarctation hasn't been noticed in follow-up of the patients. Conclusion: Surgical repair of aortaic coarctation in the adult has low-risk, and it is an effective method in decreasing the sistolic hypertension and lessens requirement of antihypertensive medications and clinical symptoms.