Abstract
Intraoperative cell salvage (IOCS) minimizes exposure to donor blood. However, the process removes plasma and platelets and may worsen the coagulopathy induced by heparinization and cardiopulmonary bypass (CPB). Accordingly, we undertook a prospective observational study to examine the changes in coagulation parameters following the retransfusion of IOCS blood.
Highlights
It has been suggested that mild hypothermia during cardiopulmonary bypass (CPB) may attenuate, but not completely suppress, the production of interleukin-8 (IL-8) in the brain [1]
Esmolol does reduce the incidence of myocardial ischaemia in association with tracheal extubation following coronary artery surgery
We examine the extent of renal glomerular and tubular injury in lowrisk patients undergoing either OPCAB or on-pump coronary artery bypass (ONCAB)
Summary
It has been suggested that mild hypothermia during cardiopulmonary bypass (CPB) may attenuate, but not completely suppress, the production of interleukin-8 (IL-8) in the brain [1]. Patients who develop SMI during tracheal extubation are more likely to have a higher heart rate [1,2] and arterial pressure [2]. The aim of this study was to determine whether an esmolol infusion could affect the incidence of SMI during the weaning from intermittent positive pressure ventilation and tracheal extubation following coronary artery surgery. Conclusions: Esmolol does reduce the incidence of myocardial ischaemia in association with tracheal extubation following coronary artery surgery. We examine the extent of renal glomerular and tubular injury in lowrisk patients undergoing either OPCAB or on-pump coronary artery bypass (ONCAB). Objective: The aim of this in vitro laboratory study was to compare the binding of propofol to different oxygenator membranes, and to examine the effects of the type of prime solution and temperature on the rate of binding. Temperature had little effect on propofol binding in either prime solution type
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