Abstract

The effect of zinc was studied on isolated frog gastrocnemius muscle wich was stimulated directly or indirectly and perfused with frog Ringer containing calcium(Ca2+) or deplated of Ca2 +. N.ischiadicus-gastrocnemius muscles were obtained from 15 frogs. Isometric force generated in response to supramaximal electrical stimulation was measured with a transducer and peak tension(Pt), contraction time(CT) and total contraction time(TCT) were analyzed by a polygraphic system and a computer. Zinc increased Pt in a concentration dependent manner, but no change was observed in er and total contraction time. We suggested that zinc might affect the striated muscle by intracellular mechanism(s).

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