Abstract
Examination of desmosomes in the spinous region of the epidermis of human skin reveals that the trilaminar structure, usually associated with desmosomes, is not always observed. Desmosomes were examined utilizing serial sectioning and tilting techniques to determine if the trilaminar structure is consistant throughout the desmosome. Concomitantly, information concerning the size and shape of the spinous layer desmosomes was obtained from examination of serial sections that completely transversed many desmosomes.Figures 1 and 2 are from a serial section series and demonstrate that the trilaminar structure of desmosomes (Dl and D2) can be observed in one section (figure 1) and not observed in an adjacent section (figure 2). Figure 3 thru Figure 6 are micrographs of the same section seen in Figure 2. These micrographs show the effect on the appearance of desmosomes Dl and D2 when they have been tilted about their longitudinal axes 5, 10, 20, and 30 degrees, respectively.
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Schedule a callMore From: Proceedings, annual meeting, Electron Microscopy Society of America
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