The effect of veratrum viride on the urine volume, blood pressure and pulse rate in normal and toxemic pregnancy

Abstract

1.1. Eight pre-eclamptic, two eclamptic, three hypertensive and four normal pregnant patients were studied in control, veratrum viride, and combined periods.2.2. The following changes were observed: 2.1.a. Normal pregnant patients showed no alteration in urine volume or blood pressure following the administration of veratrum viride.2.2.b. Pre-eclamptic and hypertensive patients showed a slight decrease in the hourly urine volume following large doses of veratrum viride. A compensatory polyuria occurred thereafter, maintaining the total output for both periods in the same proportion.2.3.c. No decrease in the urine volume was observed in the combined period.3.3. The urea clearance test showed oscillations which were considered within the range of normal variability of the test.4.4. A possible correlation between the variation in urine volume and the fall in blood pressure and pulse rate is discussed.