Abstract

The effect of seven steroids (d-norgestrel, R-5020, norethindrone, equilenin, megestrol acetate, estriol and R-2323) on corpus luteum function was assessed by their effect on the progesterone secretion rate of the autotransplanted ovary of the ewe. Only d-norgestrel (100 μg/h for 8 h) and R-5020 (100 μg/h for 8 h) proved effective in markedly suppressing progesterone output from the ovary.

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