The effect of ultraviolet radiation of pancreatic exocrine cells in mole rats: An ultrastructural study

Abstract

The purpose of this study was to investigate the ultrastructural effects of ultraviolet C (UVC) radiation on the pancreatic exocrine cells of mole rats. The mole rats were divided into two groups as control and test groups. Control group did not receive any radiation. The other group was irradiated with UV radiation for 14 and 28 days. The pancreatic tissue samples were prepared and then analyzed through transmission electron microscope. Depending on the radiation exposure, it is likely to say that the zymogen granules decreased to more than 70 per cent for the control group and the dilation of rough endoplasmic reticulum and vacuolization of mitochondria increased in the pancreatic exocrine cells at the 14 days of radiation as compared with the control group; however, they were easily observed in the 28 days of radiation exposure. Particularly in the 28 days of radiation, the zymogen granules decreased and vacuolated, and the rough endoplasmic reticulum was frequently shortened and dilated. These findings clearly demonstrated the effects of UVC radiation on pancreatic exocrine cells in an exposure-period dependent manner.