The effect of type 2 diabetes mellitus (DM) on bladder contractility in diabetic men

Abstract

Aims: To clarify the effect of DM type 2 on bladder contractility in type 2 diabetic patients. Methods: Patients (60 adult male patients) with lower urinary tract symptoms (LUTS) underwent a detailed urodynamic investigation. Urodynamic findings were classified as diabetic cystopathy [DC, characterized by impaired bladder sensation, increased post-void residual urine (PVR) and increased bladder capacity and decreased bladder contractility], detrusor overactivity. Results: All the patients in the diabetic group had type 2 diabetes mellitus for average 14 years and only 9/60 patients(15% of the diabetic group) has weak detrusor contractility their BCI less than 100. The rest of diabetic group 51/60 (85%) had good detrusor contractility. This means that diabetes (even with long duration>10 years) does not affect the detrusor contractility in our diabetic patients. 30 patients of the group (50%) had increased cystometric capacity (>450 CC),12 patients (20%) had reduced cystometric capacity (<250CC) while the rest of the patients(18 patients i.e. 30%) had average cystometric capacity(300 :450CC). 30 patients of the group (50%) had increased post voiding residual urine volume (PVR)(PVR up to 500 CC),while 30 patients of the group (50%)had normal PVR(<100CC).