Abstract

ed with the disease. Before reviewing some of the effects of treatment on glaucoma, I want to mention some of the problems that relate to any study of the effects of treatment of this disease. First of all, we have only limited information on the natural course of the disease. An estimated 1%) of patients with ocular hypertension (OHT) per year progress to primary open-angle glaucoma (POAG). However, these follow-up studies of patients with OHT involve patients with pressures under 30 mm Hg. We have no information on untreated OHT in patients with pressures of over 30 mm Hg or on untreated POAG with the exception of

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