Abstract
Transcatheter Mitral Valve Repair (TMVr) offers clinically significant benefit to select symptomatic patients with severe mitral regurgitation (MR). We conducted a systematic review and meta-analysis of clinical trials and observational studies to identify the effect of pre-procedural Chronic Kidney disease (CKD) on short-term mortality in TMVr. We found CKD is a predictor of 30-day mortality in patients undergoing TMVr. Specifically, a GFR < 30 mL/min conveys a significant increase in 30-day mortality. This is significant for patient selection, prognostication, as well as identifies an area of need for further research. Summary for annotated table of contentsA systematic review and meta-analysis looking at short-term mortality in patients undergoing Transcatheter Mitral Valve Repair with chronic kidney disease. Findings show severe renal disease is associated with increased 30-day mortality.
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