Abstract
The bone response to different titanium plasma-sprayed implants was evaluated in a goat model. Therefore, beam-shaped implants were installed into the trabecular femoral condyles of 10 goats. These implants were provided with three different titanium plasma-sprayed coatings (Ti2, Ti3 and Ti4) with a Ra of 16.5, 21.4 and 37.9 μm, respectively. An Al 2O 3 grit-blasted implant (Ti-un) with a Ra of 4.7 μm was used as control. After an implantation period of 3 months, the implants were evaluated histologically and histomorphometrically. Only one implant (Ti3) was not recovered after the evaluation period. Light microscopy showed a limited amount of bone for the various implants. Most of the implants showed a different degree of fibrous tissue alternating with direct bone contact. Complete fibrous encapsulation of the implants was observed in some of the sections. No signs of delamination of the plasma-sprayed coating was visible. No significant difference in bone contact were measured between the different types of implants ( P>0.05). Histomorphometrical analysis revealed significantly higher bone mass close to the implant (0–500 μm) for the Ti3, Ti4 and Ti-un implants placed in the medial femoral condyle and the Ti4 implants placed in the lateral condyle. At distance (500–1500 μm), no difference in bone mass measurements between the different implants was observed ( P>0.05).
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