Abstract

AbstractThe effect of incorporation of titanium oxide (TiO2) and hydroxyapatite (HA) on the mechanical properties of wollastonite (CaSiO3) was investigated in this study. TiO2/CaSiO3/HA composites ...

Highlights

  • Bone-related diseases as well as injuries have become quite frequent in recent times

  • The release of ions from calcium silicates could promote gene expression and aid in the efficiency of insulin-like growth factor (IGF) which is related to cell proliferation

  • The value obtained was proved to be a significant increase from the theoretical value of density for wollastonite (2.90 g/cm3) (Aly et al, 2016), approximately 8.6% higher

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Summary

Introduction

Bone-related diseases as well as injuries have become quite frequent in recent times. Bones are under a lot of stress, especially load-bearing bones such as the femur and tibia, and as a result the bone fractures and the surrounding tissues are damaged. This has lead to researchers attempting to develop a biomaterial which is capable of imitating a real bone in terms of durability and reliability (Garcia, Miranzo, & Sainz, 2018). Wollastonite is seen as a promising biomaterial due to its properties such as biocompatibility with human cells, compatibility with hard tissues as well as not being toxic (Lin et al, 2005; MagallanesPerdomo et al, 2010; Risbud, Saheb, Jog, & Bhonde, 2001; Tamimi et al, 2008; Zhang, Molenda, Fournelle, Murphy, & Sahai, 2010). TiO2/CaSiO3/HA composites were prepared and characterized by means of physical and mechanical properties

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