The Effect of Thrombocytopenia in COVID-19 Patient in Comparison with Patient with Normal Platelets Count

Abstract

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel coronavirus disease 2019 (COVID-19), which spreads rapidly around the world17.Changes in platelet count are common in COVID-19 patients. The platelet count is a sensitive indicator of illness severity that is of great clinical utility to monitor a quickly changing health condition of patients affected by aggressive viral infections.18 Aim of the Work study thrombocytopenia as a prognostic factor in covid 19 patient and it’s relation with length of hospital stay and prognosis Patients and Methods A total of 60 COVID-19 patients were involved in the prospective study during the period from June 2020 to December 2020 who were admitted isolation hospital, Ain Sham University Hospitals. then for each patient, CBC at admission was done, repeated at day 7 from the start of symptoms, day 14 and day 21. all patient didnot recieve anticoagulation. patients were followed regarding length of hospital stay and Mortality. Results Out of 60 patients, 19 patients (31.7%) were thrombocytopenic.The length of hospital stay was significantly higher in thrombocytopenic group. There was high statistical significant difference between normal platelets count group and thrombocytopenic groups regarding outcome (P value <0.001).in thrombocytopenic patients, 5 (50%) showed deterioration, 4 (40%) patients died and one patient in this group showed complete recovery. Conclusion Thrombocytopenia is associated with increase length of hospital stay and poor prognosis in patients with COVID-19.