The effect of threshold macular lesions and subthreshold macular exposures on visual acuity in the Rhesus monkey.

Abstract

The purpose of this research program was to evaluate retinal threshold burns and subthreshold exposures of the mammalian macula in terms of visual acuity. Rhesus monkeys {Macaca mulatto) were trained by a reward system to respond to the automated presentation of Landolt rings. After appropriate training, these animals were exposed to threshold and subthreshold levels of retinal energy density ranging from 3.2 to 10.7 J/cm2, exposure time approximately 135 ms. spectral quality approximately that of color temperature 6000° K with wavelengths above 900 nm removed,, and image sizes on the retina of about 1 mm in diameter, covering a major portion of the monkey macular area. Results, in terms of visual acuity decrement (monocular), indicated that energy densities on the retina below 5 J/cm2 were not statistically significant, whereas energy densities greater than 5 J/cm2 produced losses in visual acuity (monocular) which were significant. These results indicate that, at levels of energy density on the retina w...