Abstract
Spontaneous contractions of isolated guinea-pig atria were arrested in a potassium free medium. But, the time required to arrest atrial contractions was prolonged, when the potassium free medium contained thiamine tetra-hydrofurfuryldisulfide (TTFD). Dimethialium propyldisulfide (DMPD) showed the similar effect, while thiamine or thiamine pyrophosphate (TPP) did scarcely. Potassium content in the atria kept in a potassium free medium reduced, but the reduction was prevented by the presence of TTFD contained in the medium. DMPD, thiamine, or TPP could hardly show the similar effect. TTFD is a derivative of thiamine and has a disulfide form in its chemical structure. These specialities were assumed to bring about the above two kinds of effects of TTFD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
