Abstract
The effect of subject choice upon the physiological response accompanying a depriving experience has been studied on two occasions utilizing changes in plasma free fatty acid (FFA) levels as in index to the magnitude of neurohumoral activity. Those individuals who were asked to extend a 16 hr fast to a 24 hr fast in an arbitrary manner (subjects given least choice) demonstrated significantly greater rises in FFA level than those subjects approached in a permissive manner (subjects given high choice). The degree of hunger reported was greater at the end of the 24 hr fast for those subjects who were given the least choice. The implication of these experimental laboratory studies for the more general problem of the effect of the doctor-patient relationship upon patient response to varying types of clinical management is briefly reviewed.
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