The effect of the combined use of the mineral feed additive "Calvolit" and the probiotic additive Biolatic G-500 on the clinical blood parameters of calves with nonspecific dyspepsia

Abstract

Nonspecific dyspepsia is a common pathology of the early neonatal period, characterized by widespread and severe course, severe intoxication and dehydration. Due to diarrheal syndrome, leukocytes, immunoglobulins, water, macro- and microelements are excreted from the body of young animals. It is possible to restore the lack of inorganic substances by introducing mineral supplements into the treatment regimen, and normalize the digestive processes through the use of probiotics. Considering that the data from their combined use in the treatment of nonspecific dyspepsia of young animals are extremely scarce and sometimes contradictory, the goal was set to establish the degree of influence of the combined use of the mineral feed additive "Calvolit" and the probiotic supplement Biolatic G–500 on the main clinical blood parameters of calves in the treatment of nonspecific dyspepsia. The object of the study was 30 calves of a three-day-old black-and-white Holstein breed, selected according to the principle of pairs of analogues that had a body weight from 30.0 to 35.0 kg at birth. Three groups were formed from them. The first (control) group (n=10) included healthy animals (normotrophics) with no clinical signs of dyspepsia. The second (n=10) and third (n=10) groups were formed from animals with a characteristic clinical picture of a simple form of dyspepsia. The animals of the second group were assigned a treatment regimen used on the farm. In addition, Biolatic G-500 preparations at a dose of 5.0 g (0.5 tablespoons) and the mineral feed additive Calvolit at a dose of 30.0 g per head per day were introduced into the treatment regimen for animals of the third group. The control of the clinical condition of the animals was carried out taking into account the clinical blood test. It was found that the combined use of the probiotic drug "Biolatic" (Biolatic) G-500 and the mineral feed additive "Calvolit" as part of the treatment regimens for nonspecific dyspepsia contributes to the acceleration of normalization of clinical blood parameters and leukocyte profile of young animals.