Abstract
IT HAS been demonstrated that pituitary tumors, particularly chromophobe adenomas, can be produced experimentally in animals by prolonged administration of estrogens. This was shown by Cramer and Horning (1), Zondek (2, 3), and Wolfe and Wright (4). Experimental evidence has also been presented by Wolfe and Hamilton (5, 6) that androgens have an inhibitory effect on estrogens in pituitary physiology. However, the value of androgens in ameliorating the symptoms of intracranial pressure caused by a chromophobe adenoma in man has not yet been demonstrated. The case described here is of interest because of the possible inhibitory effect of testosterone propionate on a pituitary tumor, clinically of the chromophobe type. CASE REPORT The patient, W. J., (Fig. 1) a eunuchoid male, 24 years of age, was admitted to the Endocrine Clinic of the Pasadena Dispensary on March 24,1939. He stated that he had had normal development and hair growth at 15 years of age, having been examined by a school physician at that time...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of Clinical Endocrinology & Metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
