The effect of temperature on the inhibition of trout, carp and human red cell hexokinase by triethyltin bromide

Abstract

1. 1. At temperatures below 20°C, brook and rainbow trout red cell hexokinases demonstrate sensitivity to the inhibitory effects of triethyltin bromide. 2. 2. When the incubation temperature was raised to above 25°C, carp and human red cell enzymes were affected. 3. 3. Arrhenius plots indicated that the ΔH ∗ of the reaction was about 11 kcal for the trout enzymes and 40 kcal for the carp and human enzymes. 4. 4. The differential temperature sensitivity of the trout and human enzymes to triethyltin is correlated with the temperature sensitivity of the corresponding red cells toward the hemolytic effect of the reagent.