Abstract
The effect of electrical stimulation of the cervical sympathetic nerve on the outflow facility of aqueous humor in normal and cocaine pretreated rabbits is reported. Outflow facility was determined using the pressure decay curve technique. A significant increase in outflow facility resulting from stimulation in the cocaine pretreated animals was observed; the increase could be prevented by an intravitreous injection of phentolamine. The results of this study provide further evidence for the presence of an alpha-adrenergic mechanism involved in the outflow of aqueous humor in the rabbit eye.
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