Abstract
Abstract The bactericidal activity of experimental aqueous suspensions of light kaolin with m-cresol as preservative agreed closely with the activity of aqueous m-cresol solutions not brought into contact with kaolin (i.e. aqueous reference solutions). In contrast the activity of light kaolin suspensions with benzalkonium chloride was lower than that of aqueous benzalkonium chloride solutions because of adsorption of preservative by the kaolin. Suspensions containing benzalkonium chloride possessed a greater activity than the corresponding supernatant solutions removed from contact with the kaolin, owing to some of the bactericide adsorbed on the kaolin becoming available to the bacteria. Suspensions of procaine penicillin with benzalkonium chloride gave similar results to those for kaolin.
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