Abstract

Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. It is well known that a stiffened artery can be associated with various diseases and with aging. Usually, PWV is measured using the foot-to-foot method. The foot of the pressure wave is not clear due to reflected waves and blood noise. Also, PWV is an average indicator of artery stiffness between the two measuring points, and therefore does not identify local stiffness variations. PWV is directly related to the Young's modulus in the circumferential direction of the artery by the well known Moens-Korteweg equation. However, in this famous equation, PWV only relates to the artery properties and blood density, but does not relate to the surrounding tissue. The objective of this paper is to develop method for studying the surrounding tissue effect on the arterial waves. It is found that the short pulse wave generated by ultrasound in the artery travels faster if the artery is embedded in gelatin, which means that the gelatin stiffens the artery.

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