Abstract

Background: The effect of resistant exercise program on controlling metabolic abnormality and improving chronic complication risk factors has not been extensively studied in Type 2 Diabetes Mellitus patients in Ethiopian context. Objective: The objective of this study is to determine the effect of supervised Progressive Resistance Training (PRT) protocol on weight loss, body composition, glycemic control and cardio vascular disease (CVD) risk markers reduction to prevent and control Type 2 diabetic complications. Methodology: We did a 12-week Prospective follow-up for adult Ethiopians with Type 2 diabetes (mean age of 48.15±6.8yrs) assigned to supervise PRT at the University of Gondar Hospital, North West Ethiopia. Using convenience sampling, we select 22 DM patients. Of the 22 subjects recruited for experiment, 2 withdrew following the intervention. Glycemic control, CVD risk markers and body compositions were determined before and after the intervention. Weight, body composition, fasting blood glucose, low density lipoprotein (LDL) and total cholesterol, were used as the main outcome measures. Results: Only 20 study subjects completed the 12-week PRT (three times per week) before (Baseline) and after the intervention the PRT reduced fasting blood glucose (FBG) (28.1%), T. cholesterol (12.9%), triglycerides (33.1%), resting pulse rate( 9.9%), resting systolic blood pressure (11.4%), resting diastolic blood pressure (6.9%), weight (1.9 %), BMI (2.5%), body fat percentage (9.7%). There was an increase in muscle and bone density (1.5 %) p 0.5) Conclusion: Supervised PRT for 12 weeks resulted in a significant improvement in glycemic and blood pressure control, Dis-lipidmia and body composition of Type 2 diabetes patients. There is now suggestive evidence supporting the use of moderate intensity PRT for improving glycemic control in DM in Ethiopia.

Highlights

  • The term diabetes mellitus (DM) describes a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both [1]

  • Supervised Progressive Resistance Training (PRT) for 12 weeks resulted in a significant improvement in glycemic and blood pressure control, Dis-lipidmia and body composition of Type 2 diabetes patients

  • There is suggestive evidence supporting the use of moderate intensity PRT for improving glycemic control in DM in Ethiopia

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Summary

Introduction

The term diabetes mellitus (DM) describes a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both [1]. According to the World Health Organization (WHO) estimate, the global burden of diabetes has increased from 177 million people in the year 2000 to194 million in 2003 and further to 246 million people in 2007 [1]. According to an extrapolated data the prevalence of DM in Ethiopia was 2.5 % in the year 2000 which is estimated to rise to 3.5 % by 2030 [4]. Like any other prescription (drug), has type and dose, that is, a dosing frequency, duration of treatment, therapeutic goal and anticipated adverse effects [5]. The effect of resistant exercise program on controlling metabolic abnormality and improving chronic complication risk factors has not been extensively studied in Type 2 Diabetes Mellitus patients in Ethiopian context

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