The effect of subacute intoxication of monensin on minerals and trace elements in goats

Abstract

The aim of this study was to evaluate the status of minerals and trace element concentrations in serum samples from goats with subacute intoxication of monensin. For this purpose, monensin with the dose of 13 mg/kg boy weight was orally administered to seven goats for 5 consecutive days. Elements including sodium (Na), potassium (K), Calcium (Ca), magnesium (Mg), phosphorous (P), iron (Fe), copper (Cu), zinc (Zn), and selenium (Se) were determined in baseline and daily serum samples for 10 days. Subacute monensin intoxication significantly decreased serum concentration of Ca, Mg, Na, and Zn in most of samples. Serum concentration of P significantly increased at days 2 and 7–10. There was no significant change in serum concentration of Fe, Se, and Cu during the experiment. These finding indicate that subacute monensin intoxication alters serum concentrations of minerals and certain trace elements in goats.