Abstract
The stellate ganglia (STG) of cats were removed under general anesthesia either on the left, or right or on both sides. Eight to ten days later H 3-norepinephrine (H 3-NE) was injected intravenously and the cats sacrificed 2 hr later. The hearts were removed and dissected into right and left atria and ventricles and into atrial septum and ventricular septum. The parts were weighed, homogenized in perchloric acid and the total catecholamines (CA) as well as the H 3-NE determined in the eluates of aluminium oxyd columns. The removal of the left STG reduced the concentration of the endogenous CA only in the left atrium and ventricle. The removal of the right STG reduced the endogenous CA concentration in all parts of the heart. The removal of both STG showed a further decrease in the endogenous CA concentrations. In all parts of the heart, where the extirpation of the STG caused a decrease in the endogenous CA content, the uptake and binding of H 3-NE was also diminished. The influence of sympathetic innervation on the uptake and binding capacity of NE is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.