Abstract
ABSTRACT The effect of soy protein with low calorie diet on blood lipids in hyperlipidemic type 2 diabetic patients was studied. Thirty‐two subjects of both sexes, age range 25–65 years, were distributed in 16 cases and 16 controls. All subjects received a low calorie diet based on 1,400 kcal energy, 27% fat, 21% protein and 52% carbohydrate from a registered dietitian for 4 weeks. In addition to a low calorie diet, the case group received soy protein (30 g/d). Both groups significantly lost weight (P < 0.001). Body mass index, waist and hip circumferences were significantly reduced (P < 0.05) after 4 weeks of treatment. The difference between the groups was insignificant. In all subjects who were fasting, blood sugar significantly decreased (P < 0.001). Soy protein was associated with a significant reduction in serum triacylglycerols (24.8%, P < 0.05), whereas an insignificant reduction was seen in total cholesterol and low‐density lipoprotein (7.1 and 3.1%, respectively). No significant change occurred in high‐density lipoprotein cholesterol.PRACTICAL APPLICATIONSSerum lipid abnormalities are an established risk factor for cardiovascular disease in diabetic patients. Because of the side effects of long‐term medications in these patients, soy protein, as a part of healthy diet, may improve their lipid profile.
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