Abstract
AbstractAs part of an extensive study on insect antijuvenile hormones (AJH) structurally related to 2,2‐dimethyl‐7‐methoxychromene and 6,7‐dimeth‐oxy‐2,2‐dimethylchromene (precocenes I and II, respectively), four furophenols, six furochromenes, three benzofuran derivatives and two benzochromenes were tested for biological effects on Oncopeltus fasciatus and Locusta migratoria. Exposure to ajar deposit of the chemical was used for O. fasciatus and topical application in acetone for L. migratoria, with precocenes I and II as standards for comparison. All compounds were toxic to O. fasciatus and in some cases, this may have concealed any potential AJH activity, which was not observed for any compound tested. Toxicity to L. migratoria was less evident and three of the furochromene derivatives, allprecocene‐I (PI) analogues, showed AJH activity seven to ten‐fold lower than that of PI. Neither of the benzochromenes tested showed any AJH activity. The results are discussed in terms of the known structure‐activity relationships for precocene‐like AJH activity.
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