The Effect of Some Factors on Virulence of E.coli Bacteria Isolated from UTI Infection. (Review study)

Abstract

The study aims to demonstrate the effect of some traits on the virulence of E.coli bacteria, the important of which are the number and type of bacterial isolates, their sensitivity to some antibiotics and the production of the β-lactamase enzyme. We adopted in this research a multi-studies relative to some countries and different governorates inside Iraq to show the prevalence range of this gender and its great impact on urinary tract infection. It was found through various previous studies that E.coli is present in a large extent in the urinary tract compared to other isolates, as it is a suitable environment for causing infection after seizing the opportunity and reaching to the urinary tract after ascending from the digestive system, which are endemic organisms in which the normal flora. And it is found more often in women than in men for physiological reasons.It also contains multiple resistance to MDR antibiotics. This resistance may be depend on the presence of the plasmid that carries the genetic information to produce the enzyme β-lactamase, which works to break the β-lactamase cycle and create the bio resistance to the antibiotic. This resistance varies from gender to another and from one environment to another. Various studies around the world, especially penicillin’s, the difference in the degree of sensitivity to this antibiotic or the degree of resistance according to the place in which the patient is located and according to the manufacture of the antibiotic and its chemical composition. This type of infection depends on its rapid identification and taking the appropriate antibiotic as soon as possible and for the required time, lest it lead to other complications, the most important of which is the kidney failure caused by this genus, and it is preferable to make a sensitivity test for antibiotics in order to be able to determine the appropriate antibiotic.