Abstract

Experiments were stated on albino rats and guinea pigs with a common bile duct fistula. The effect of enzymatic poisons on bile secretion, its qualitative composition and bromsulfalein (BSF) excretion were studied. Sodium fluoride monoiodacetic acid (MIA) and 2,4-dinitrophenol decrease bile secretion; 2,4-dinitrophenol has no effect on bilirubin and BSF bile excretion, whereas MIA and sodium fluoride inhibit these processes. MIA considerably reduces the bile concentration of bile acids.

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