The Effect of Some Biochemical and Physiological Parameters in Iraqi Patients with Renal Failure

Ahmed Ali Khesbak ,Jaafar Khalaf Ali ,Mohammad Abdulbaqi Abdulmohsin

doi:10.7176/jbah/10-14-04

Abstract

Background: Renal failure occur when the kidneys are unable to bring out the body's metabolic wastes or proceed their regulatory assignment. Objective The study was designed to compere some biochemical and hematological parameters in patents with renal failure and control group. Patients and materials: A case-control study was conducted from September 2018 t0 April 2019 on patients attending the artificial Kidney Unit in Al-Hussein Hospital in holy Karbala Governorate. A total of fifty known cases of renal failure and fifty health persons were selected. Blood samples were taken from both (patients and control) to estimate biochemical and hematological parameters by using specific methods. Results: the results of this study found the high increase (P˂0.05) in concentration of blood urea, serum creatinine, and calcium levels, a significant decreases (P ≤ 0.05) in (Hb) and (PCV) in patients while (ESR) rate were significantly increased (P ≤ 0.05) in these patients when compared to healthy control. Conclusion: In this study conclude that the biochemical parameters are more efficient than hematological parameters in follow-up cases of patients with renal failure. Keywords: Renal failure, parameters, Urea, Creatinine, Calcium. DOI: 10.7176/JBAH/10-14-04 Publication date: July 31 st 2020

Highlights

ObjectiveThe study was designed to compere some biochemical and hematological parameters in patents with renal failure and control group
Kidney failure is a disease in which the kidneys may not remove metabolic end-products from the blood and regulate the extracellular fluid's fluid, oxidation and PH level
Unlike (ARF) acute renal failure, which begins rapidly and abruptly, Chronic renal failure (CRF) occurs slowly over a period of weeks, months or years[4],if the kidneys perform at less than 10% of their normal capacity, i.e. glomerular filtration rate (GFR) is less than 15 ml / min/1.73 m2 and chronic renal failure occurs at the end-stage renal disease (ESRD) [5]"

Summary

Objective

The study was designed to compere some biochemical and hematological parameters in patents with renal failure and control group. Patients and materials: A case-control study was conducted from September 2018 t0 April 2019 on patients attending the artificial Kidney Unit in Al-Hussein Hospital in holy Karbala Governorate. Blood samples were taken from both (patients and control) to estimate biochemical and hematological parameters by using specific methods. Results: the results of this study found the high increase (P0.05) in concentration of blood urea, serum creatinine, and calcium levels, a significant decreases (P ≤ 0.05) in (Hb) and (PCV) in patients while (ESR) rate were significantly increased (P ≤ 0.05) in these patients when compared to healthy control. Conclusion: In this study conclude that the biochemical parameters are more efficient than hematological parameters in follow-up cases of patients with renal failure.

Introduction

3- Result

Findings

Conclusion