Abstract
In relation to a previous paper (J. Antibiotics 32: 734-739, 1979), the effect of some antibiotics on endogenous phospholipid degradation of rat liver was investigated by slice and perfusion techniques. Polymyxin B inhibited this degradation most strongly, benzylpenicillin, chloramphenicol and peplomycin inhibited moderately, and carbenicillin, cephaloridine and streptomycin did not inhibit. Tetracaine and ethylenediaminetetraacetic acid, which are not antibiotics, also showed inhibitory effects. The results strongly suggest that besides their usual antibiotic actions, some antibiotics may participate in endogenous phospholipid metabolism and biomembrane functions of host cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
