Abstract
For the first time, the effect of inflammation on the degradation of Mg and Fe was evaluated. The immersion test and electrochemical approaches were carried out under simulated inflammatory condition, with CoCrMo alloy selected as the reference. It turned out that H2O2, the major reactive oxygen species released in the inflammation, changed the surface film behavior of pure Mg and CoCrMo alloy for the initial exposure in PBS, but insignificantly affected their corrosion during the long-term immersion. By contrast, H2O2 actively participated in the degradation of pure Fe in a concentration-relevant manner, notably accelerated the Fe corrosion, and inhibited the corrosion product formation during 14-day immersion. It’s suggested that inflammation induced corrosion should be taken into consideration in evaluating biodegradable metals.
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