Abstract

Due to a high number of bone fracture cases in Indonesia, the development of bone scaffold is becoming a solution to improve damaged bone structure. In bone scaffold fabrication, several parameters must be met such as morphology, pore size, and antibacterial properties. One of the antibacterial agents that can be used for the bone scaffold is silver nitrate (AgNO3). In this study AgNO3 with various concentrations (0.005, 0.01, 0.02, and 0.1 M) was added in HA-chitosan bone scaffold that was synthesized via freeze drying process. The synthesis resulted in bone scaffolds in the form of an interconnected porous structure. In this study, Fourier transform infrared (FTIR), scanning electron microscope (SEM), energy dispersive x-ray (EDX), and antibacterial test were carried out. SEM-EDX results showed porous morphology with an average size of 68.32 µm in bone scaffold without AgNO3 and 16.66 µm in the bone scaffold with the addition of AgNO3. Antibacterial testing showed that the higher the concentration of silver nitrate used, the greater the diameter of the inhibitory zone produced.

Full Text

Published Version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.