Abstract

This systematic review updates the current state of evidence on the effectiveness of softer flooring and cushioned shoe insoles on reducing musculoskeletal discomfort amongst workers who are required to stand for prolonged periods to work and the impact of factors such as age and gender on the outcomes. A systematic search identified 10 unique studies that met the eligibility criteria. The heterogeneity of study designs impacted on the strength of evidence. A moderate level of evidence was found in support of using cushioned materials in reducing discomfort/fatigue among standing workers. A limited level of evidence exists in favour of using insoles over anti-fatigue mats. Insufficient information exists for the impact of gender or age. Larger, good quality prospective intervention trials based in real workplaces that consider the impact of psychosocial and organisational factors on musculoskeletal discomfort whilst standing at work are required to inform industry recommendations.

Highlights

  • Elevated serum triglyceride concentration or in other words hypertriglyceridemia (HTG) is common in the populations of developed countries

  • In 13 publications, serum triglyceride concentration (seTG) were defined inappropriately (e.g.

  • We investigated the effect of different seTGs on the outcome of acute pancreatitis (AP)

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Summary

Introduction

Elevated serum triglyceride concentration (seTG, >1.7 mM or >150 mg/dL) or in other words hypertriglyceridemia (HTG) is common in the populations of developed countries This condition is accompanied by an increased risk for various diseases, such as acute pancreatitis (AP). It has been proposed that HTG could worsen the course of AP In this meta-analysis, we aimed to compare the effects of various seTGs on the severity, mortality, local and systemic complications of AP, and on intensive care unit admission. The extent of HTG has been classified by the Endocrine Society into the following groups based on fasting seTG: mild (1.7 to 2.3 mM), moderate (2.3 to 11.2 mM), severe (11.3 to 22.4 mM) and very severe HTG (>22.4 mM)[4].

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