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Abstract
The objective of this study was to determine the effects of serum-based bioactive proteins on the prevention of squamous gastric ulcer formation in horses in moderate exercise programs over a 21-day period. Horses without ulcers were identified and randomly assigned to treatment or control group. Horses were subjected to a training program which induced squamous gastric ulceration in control horses. In horses treated with 210-g bioactive proteins, the incidence of squamous ulcers was significantly reduced (P = .0001) compared to control horses. In horses treated with 80-g bioactive proteins, 66.67% (10/15) of the control horses developed squamous gastric ulceration compared to 33.55% (5/15) of those administered bioactive proteins. In conclusion, dosing horses with bioactive proteins derived from serum was effective for preventing gastric ulcers in horses experiencing stress from exercise or training.
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