The effect of serotonin and catecholamines on the nervous control of periodic activity in fresh-water mussel ( anodonta cygnea)

Abstract

1. 1. The effect of serotonin and related compounds, catecolamines and also different pharmacons was investigated on the nervous control of periodic activity in fresh-water mussel Anodonta cygnea. 2. 2. Relaxation of the posterior adductor muscle can be induced by the action of various, physiologically active agents on the cerebral ganglia; its phasic, rhythmic function can also be increased, and, in this way, the animal's periodic activity can be influenced. 3. 3. Application of serotonin or catecholamines produces an essentially similar activity. However, to obtain the same effect, a catecholamine concentration ten times higher than that of serotonin has to be used. 4. 4. Reserpine, iproniazid and LSD produce a serotonin-like effect, while chloropromazine brings about the tonic contraction of the posterior adductor.