Abstract
Peripheral arterial occlusive disease (PAOD) is a prevalent atherosclerotic disorder characterized by exertional limb pain, loss of limb, and a high mortality rate. Because of its chronic nature, it often has a negative impact on a patient quality of life (QoL). Aims. To evaluate the effect of selected health, demographic and psychosocial aspects on QoL in respondents with PAOD. The study is a prospective and cross-sectional. It was carried out at the 2nd Department of Medicine of Charles University Hospital at the Faculty of Medicine in Hradec Králové, Czech Republic. Forty two respondents with PAOD (28 male, 14 female) were evaluated. All the respondents had involvement of femoral and popliteal arterial circulation. The number of all respondents in accordance with Fontaine classification was as follows: intermittent claudication: stage IIa - 4, stage IIb (<200 m) - 16, stage IIb (<50 m) - 9, chronic limb ischaemia: stage III - 6, stage IV - 7. The average age of all respondents was 65,4 years old (age range 45-79 years old). The study evaluates the effect of health aspects (stage of PAOD in accordance with Fontaine classification, diabetes mellitus, arterial hypertension, hyperlipidaemia, obesity, smoking), demographic (age, sex) and psychosocial aspects (level of education, marital status, religion) on QoL in respondents with PAOD. The Czech version of the International Generic European Quality of Life Questionnaire - EQ-5D was used. The statistical evaluation presents statistically a significant dependence of QoL in respondents with PAOD on age (p < 0,01) and the stage of PAOD in accordance with the Fontaine classification (p < 0,01). The effect of other health, demographic and psychosocial aspects was statistically insignificant. The results had shown that with an increasing age and with a serious stage of PAOD in accordance with Fontaine classification, the QoL declines. The global QoL in respondents with PAOD is low.
Highlights
Peripheral arterial occlusive disease (PAOD) is a prevalent atherosclerotic disorder characterized by exertional limb pain, loss of limb, and a high mortality rate [2]
We evaluated the effect of selected health aspects, demographic and psychosocial aspects on quality of life (QoL) in respondents with PAOD
The evaluation of QoL in respondents with PAOD was performed by means of the Czech version of the International Generic European Quality of Life Questionnaire – EQ-5D Version [5,6,7,8,9]
Summary
Peripheral arterial occlusive disease (PAOD) is a prevalent atherosclerotic disorder characterized by exertional limb pain, loss of limb, and a high mortality rate [2]. Intermittent claudication is the most common symptom in patients with PAOD [1]. Endovascular revascularization (artery balloon and stent angioplasty) currently serves as an effective therapy for patients with high-grade stenoses of the proximal limb arterial segments [1,2]. Surgical revascularization usually is reserved for patients who present with severe aortoiliac disease (in whom long-term patency is likely to be achieved) and who have a low cardiovascular perioperative ischemic risk. All patients with PAOD, of any severity, must successfully normalize atherosclerosis risk factors and use antiplatelet therapies [1]. PAOD as a chronic disease is associated with physical, psychological and social distress for elderly patients and their families [4]. People with PAOD have a significant disability that affects psychosocial and emotional aspects of their quality of life (QoL) [5,10]
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