Abstract
Bile flow rate and electrolyte composition as well as gastric acid secretion were studied in patients with T-tube drainage of the common bile duct, under basal conditions and during intravenous infusion of GIH secretin, pentagastrin, or histamine. Secretin infusion caused a marked increase in bile flow and in the concentration of bicarbonates. It significantly inhibited basal gastric acid output in all tested patients. Pentagastrin and histamine provoked a maximal acid secretion without apparent changes in bile flow or electrolyte composition.
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