THE EFFECT OF SAMPLING TECHNIQUE ON BACTERIOLOGICAL RESULTS IN PATIENTS WITH MALIGNANT LUNG TUMORS

Abstract

Purpose of the study: to evaluate the lower respiratory tract microflora in patients with malignant lung tumors with chronic obstructive pulmonary disease (COPD). Material and methods: sputum of patients subdivided into three groups was evaluated: main group consisting of 52 patients with malignant lung tumors without COPD; group 2 – 23 patients with malignant lung tumors and COPD; Group 3 – 25 patients without lung cancer or COPD. Results: it was found that for patients with malignant lung tumors, none of the specific methods for the isolation of microorganisms from the respiratory tract was practically significant. The most reliable data on microbiota of the lower respiratory tract could be obtained only after a omprehensive study of throat swab, sputum, bronchial aspirate/lavage and protected brush biopsy. The approach allows for a science-based antimicrobial treatment of patients suffering from lung cancer. Results of the in-depth bacteriological study are especially relevant in the treatment of patients with lung tumors and COPD, for the most of whom adequate antimicrobial chemotherapy is vital.