Abstract
Diabetes Mellitus (DM) is considered a very common health problem today. It causes many acute and chronic complications and negatively affects the quality of life of patients. It is known that diabetes has an impact on many biochemical processes. This study aimed to evaluate the interaction between royal jelly (RJ) and diabetes with irisin, a parameter that has not been investigated before. The study was planned with 3 groups: control group, DM group, DM+350 mg/kg RJ group. In the experiments, 18 female Wistar albino rats were studied. Irisin levels in rat blood serum were determined using the ELISA (Enzyme-Linked Immuno Sorbent Assay) method. Glucose levels in blood taken from the tail vein were determined with a glucometer. As a result of the experimental study, a statistically significant difference was found in the DM+350 mg/kg RJ group compared to the control group (p
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