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Abstract
IT was found in a previous study (1) that exposure of growing dog bone to moderate doses of roentgen rays is followed by a period of lowered phosphatase activity beginning a few days after exposure and showing a tendency to return to normal after from three to five weeks. Since the enzyme phosphatase is so widely distributed in the animal body it was felt that a study of the phosphatase activity of the entire body after exposure to x-rays would be of interest. Also, we desired to determine the concentration of certain electrolytes, some of which are known to influence the activity of the enzyme. Loiseleur and Van der Schueren (2) and Adler and Wiederhold (3) have studied the metabolism of several inorganic substances in the rabbit following x-ray irradiation. Kinard and Chanutin (4) found that the phosphatase activity of the whole rat was increased following large doses of irradiated ergosterol. Analytical Methods.—The phosphatase determinations were made by a technic similar to that described by Jenner a...
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