The effect of retina photocoagulation through multifocal intraocular lens in rabbits

Abstract

Objective To provide reference for retina photocoagulation through multifocal-intraocular lens (MIOL) in patients.By studying retinal photocoagulation parameters and the effects after MIOL implantation in rabbit eyes. Methods Total 6 adult purple blue rabbits were included in this study.Two ZM900 MIOLs and two Rezoom MIOLs were implanted in 4 eyes separately,and 2 eyes as a comparison.Fundus fluorescein angiography (FFA) and retina Optical Coherence Tomography (OCT) were performed 1 hour,24 hours,1 week,4 weeks after retinal photocoagulation.The fluorescent leak of laser spots and retina tissue changes were observed. Results The average energy was 200.6±14.31mW in ZM900 group with 200μm spot and 219.2±3.93mW with 500μm.In Rezoom group,the average energy was 203.6±9.77mW with 200μm spot,and 206.0±9.19mW with 500μm spot.In the control group,the average energy was 116.2±14.99mW with 200μm photocoagulation spot and 133.5±4.78mW with 500μm spot.There was no statistically significance between the 200μm and 500μm spot in MIOL groups (P ＞0.05).Laser energy in control group was greater than MIOL groups,and there was statistical significance between control and MIOL group in two diameter spot (P ＜0.05).Twenty-four hours after photocoagulation,there was significant neural epithelial detachment in ZM900 group and Rezoom group,whereas detachment was not observed in the control group. Conclusions Retina photocoagulation can be successfully completed through both refraction and diffraction MIOLs,but excessive photocoagulation is observed in MIOL implanted eyes.Thus it suggests proper reduction of laser intensity for treatment patients with MIOL implantation. Key words: Multifocal intraocular lens; Retina; Photocoagulation; FFA; OCT