Abstract
To the Editor. —Capra et al 1 should be widely congratulated for their elegant study of gadolinium-pentetic acid enhancing (GAD+) lesions in 10 patients with relapsing-remitting multiple sclerosis (MS) whose serial brain and spinal cord magnetic resonance imaging (MRI) scans and neurological examinations were monitored for 3 months. This study significantly advances our understanding of GAD+ lesion activity in patients with MS because both brain and spinal cord locations were simultaneously monitored and careful attention to repositioning on serial scans was done with the assistance of a laser. However, the results of this study should be interpreted with some caution because, even with laser assistance, the potential for unavoidable small repositioning errors (
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