The effect of reduced oxygen saturation during sleep on depression

Abstract

Introduction: Numerous data suggest that episodes of breathing disorder during sleep are closely related to chronic cardiovascular and mental illnesses. Aim: In this study, we sought to find out how the decrease in oxygen saturation level and its duration during sleep are affected by the degree of depression and its extent. Method: Data of 76 persons were processed in the study. The oxygen saturation measured during sleep was obtained from data from a polysomnographic filter device. Data collection for depression symptoms was done with a validated questionnaire. The decrease of night oxygen saturation on the effect of the disease was illustrated by the odds ratio calculation. Results: The value below 90% of the average oxygen saturation during sleep time will more than double the risk of developing depression. It is also a risk factor for the severity of depression. Examining the duration of sleep time at reduced saturation, it mainly increases the chance of severe depression. Conclusions: Hypoxia during sleep and duration of hypoxic periods are a risk factor for the development of depression with therapeutic and diagnostic consequences. Orv Hetil. 2019; 160(20): 780-783.