Abstract

Introduction: P-wave dispersion (PWD) obtained from the standard 12-lead electrocardiography (ECG) is considered to reflect the homogeneity of the atrial electrical activity. The aim of this investigation was to evaluate the effect of percutaneous chronic total occlusion (CTO) revascularization on the parameters of P wave duration and PWD on ECG in cases before and after procedure at 12th months. Methods: We analyzed 90 consecutive CTO cases who were on sinus rhythm and underwent percutaneous coronary intervention (PCI). P-wave maximum (P-max) and P-wave minimum (P-min), P-wave time, and PWD were determined before and twelve months after the CTO intervention. The study population was categorized into two groups as successful and unsuccessful CTO PCI groups. Results: The CTO PCI was successful in 71% of cases (n=64) and it was unsuccessful in 29% of cases (n=26). Both groups, except for age and hypertension, were similar in terms of demographic and clinical aspects. CRP levels were significantly elevated in the unsuccessful CTO PCI group. Pre-PCI ECG parameters showed no significant difference. Irrespective of the target vessel revascularization, we observed that PWD and P-max values were significantly lower in the 12th months follow-up. In all Rentrop classes, PWD values were significantly decreased at 12th months follow-up in comparison to the pre-CTO PCI values. Conclusion: This study has determined that PWD and P-max, which are both risk factors for atrial arrhythmias, are significantly reduced within 12th months after successful CTO PCI regardless of the target vessel.

Highlights

  • P-wave dispersion (PWD) obtained from the standard 12-lead electrocardiography (ECG) is considered to reflect the homogeneity of the atrial electrical activity

  • The study cohort was categorized into two groups as successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI) (n = 64; 71%) and unsuccessful CTO PCI groups (n = 26; 29%)

  • CTO segment was mostly located in the right coronary artery (RCA; 55.6%)

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Summary

Introduction

P-wave dispersion (PWD) obtained from the standard 12-lead electrocardiography (ECG) is considered to reflect the homogeneity of the atrial electrical activity. P-wave dispersion (PWD) obtained from the standard 12-lead electrocardiography (ECG) is considered to reflect the homogeneity of the atrial electrical activity, and it appears to be quite promising in the perspective of AF prediction.[1] A prolonged duration of PWD has been reported to increase the risk of developing AF in cases without underlying heart disease.[2] AF is the commonly observed cardiac arrhythmia, with a 25% lifetime risk along with associated complications in the population, including heart failure, stroke, and death.[3] In developed countries, hypertension and coronary artery disease (CAD) are the main clinical diagnoses associated with AF. CAD causes severe ventricular ischemia leading an increase in intra-atrial pressure and AF.[4]

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