Abstract
RADIOTHERAPISTS, since the early days, have depended for therapeutic results on selectivity of their radioactive agent for certain cells of the organism. Since mature or fully differentiated tissue possesses increased resistance to irradiation, particularly to the hard beta and gamma rays of radium, the stages of cellular retrogression after exposure to these rays no doubt transpire more slowly in the adult, and thereby afford adequate time for a more accurate and comprehensive study of the consequent cellular changes. This experimental study was undertaken to determine the cellular changes which occur in the liver, a specialized parenchymatous organ, subjected to the influence of radium as contained in gold-filtered radon seeds. The white rat was selected for the experiments because large numbers are available, and because the rat is well adapted to operative procedure and laboratory confinement. In 1898, three years after the discovery of the roentgen ray, Curie submitted her thesis regarding the new el...
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