The Effect of Q10 Supplementation on Lipid and DNA Degradation Indices Following an Acute Physical Activity

Abstract

Background and Objectives The use of antioxidant supplements improves and reduces oxidative stress factors following intense intense exercise. Exhaustion was performed in female athletes. Subjects and Methods 14 female athletes with an age range of 20 to 28 years and a maximum oxygen consumption of 42-52 m/kg/min in a quasi-experimental design randomly divided into two groups receiving coenzyme Q10 supplementation and placebo (5 mg/kg body weight). Were. After 14 days of coenzyme Q10 supplementation, the subjects performed an intense, debilitating activity. Urine samples were collected in three stages (baseline, before and 24 hours after exhaustive activity) to determine the concentration of 8-OHdG and MDA. Results There was a significant difference of 62% in the increasing response of urinaryOHdG-8 to an exhausting aerobic exercise session (P = 0.003). However, the 2% difference in the increasing urinary MDA response of the supplement and placebo groups was not significant after the last quasi-competitive aerobic training session (P = 0.7). Conclusion According to the results of the study, two weeks of high-pressure aerobic training causes DNA damage and lipid peroxidation in female athletes, and supplementation with Q10 helps prevent the 8-OHdG response of female athletes after a strenuous high-pressure aerobic training session and reduces DNA damage. Become athlete