Abstract
A DDT resistant strain of house flies being reared for insecticidal tests exhibited a high degree of resistance to all chlorinated hydrocarbons to which it had been exposed. Results obtained from use of the OTI (Official Test Insecticide) in the Peet-Grady chamber indicated that this strain also showed a marked degree of resistance to pyrethrins. Though the knockdown rate was only slightly lower than that for nonresistant flies, the resulting mortality was considerably lower. Since pyrethrins and chlorinated hydrocarbons are quite dissimilar both in structure and mode of action, it was thought that the toxicity of combinations of these substances might provide some useful information. To provide an additional point of comparison flies from both the DDT resistant and nonresistant cultures were exposed to these combinations.
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