Abstract
Many dry eye patients undergo punctal occlusion to relieve the signs and symptoms of keratoconjunctivitis sicca (KCS). Punctal occlusion inhibits lacrimal fluid loss from the tear film by blocking the naso-lacrimal duct. This improves the symptoms in patients with tear-deficient dry eye, but it is unknown as to whether there is a concomitant improvement in the biochemistry of the tear film. This study analyzes tear lactoferrin levels in response to punctal occlusion in patients with tear-deficient dry eye.
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