Abstract
This paper reviewed prolotherapy as an approach to treating temporomandibular joint disorders (TMD), focusing on temporomandibular joint subluxation and hypermobility. Prolotherapy, commonly used in orthopedics, involves injecting substances like dextrose or lidocaine to promote healing in musculoskeletal conditions. Clinical studies in which this prolotherapy was used for TMD were reviewed. Total 13 papers involving 372 patients (Male 90, Female 282) were examined, considering factors such as dextrose concentration (10%~50%), injection frequency (one to four times), injection period (one to four weeks) and injection sites. The assessment primarily focused on pain reduction and changes in maximum mouth opening after prolotherapy. In all papers, a consistent trend of pain reduction after prolotherapy was observed. Regarding maximum mouth opening, there were 6 cases of decreased range and 7 cases of increased range. With prolotherapy's rec-ognition as a new medical technology for TMD, it emerges as a potential alternative treatment, highlighting its significance in the field.
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